Endocrine Abstracts

Introduction: The islets of pancreas contain relatively high levels of Gamma-amino butyric acid (GABA). This study was designed to determine the role of the GABA and GABAB receptor on glucose-stimulated insulin secretion of isolated islets in rats.Materials and methods: The Collagenase digestion technique was used to isolate the islets from male Wistar rats and insulin secretion was assessed in islets exposed to glucose (8.3, 16.7 mM) in prese...